Use Case 2: A Hospital Participates in RWE

Without Exporting Patient Data

What this looks like in practice

A regional academic medical center has 1.2 million patient records and a strong clinical informatics team. Pharma sponsors regularly ask about data partnerships. The CIO, legal, and compliance teams consistently say no. HIPAA exposure, breach risk, and reputational concerns outweigh the modest payments offered.

The old way

Sign a data use agreement. Export de-identified patient records to a sponsor or data aggregator. Hope the de-identification holds. Accept ongoing legal exposure for years. Get paid based on how many patient records left the building.

With NexusRWE

The hospital onboards once with a standard governance configuration. Sponsors submit locked study protocols. Because no patient data ever leaves, the traditional approval burden largely falls away. IRB review, HIPAA business associate agreements, and ongoing breach exposure are no longer part of the equation. The CIO, legal, and compliance teams review scope and resource allocation, not patient privacy risk. Approved studies run locally inside a secure, isolated environment. Only aggregate, privacy-protected results leave. Nothing else. The hospital is compensated for compute resources, not patient records.

The outcome

The hospital participates in regulatory-grade studies it previously had to decline. Data sovereignty is structural, not just promised. Compensation is tied to a service the hospital actually provides, not to the volume of patient data exported.