NexusRWE uses a federated query architecture: analyses run behind each hospital's firewall, on their own hardware, under their own governance. The goal is that nothing leaves the institution except encrypted, de-identified summary results.
Pre-approved, audited queries are sent to participating hospital nodes. Each query is reviewed by the institution's governance team before running.
Analysis runs entirely behind the hospital's own firewall. Patient records never leave the institution. Hospitals deploy a lightweight containerized node with no data egress required.
Only de-identified, encrypted summary results return to the coordination server. No patient-level data, no records, no identifiers.
A tamper-proof audit trail and submission package auto-assemble, structured for FDA, EMA, and PMDA requirements.